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Isaac Progression

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Unofficial fan project. Not affiliated with the developers of The Binding of Isaac.

Game facts are sourced from the Binding of Isaac Rebirth Wiki (CC BY-SA), and each guide links to its sources. Your progress is saved only in this browser.

Achievement

A Cross

Defeat Isaac as Magdalene.

In-game: “Unlocked a new item.”

Sources:Achievements Cathedral Isaac (Boss)

0 of 3 doneNext: Magdalene

x

Stage 1any order

Magdalene
Next up
Have 7 or more red heart containers at the same time.
In any run, have 7 or more red heart containers at once.
Sources:Achievements Magdalene
The Womb
Ready
Defeat Mom.

Stage 2

A Cross
Later
Defeat Isaac as Magdalene.
After: Magdalene, The Womb