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Unofficial fan project. Not affiliated with the developers of The Binding of Isaac.

Game facts are sourced from the Binding of Isaac Rebirth Wiki (CC BY-SA), and each guide links to its sources. Your progress is saved only in this browser.

Achievement

Card Against Humanity

Complete When Life Gives You Lemons (challenge #12).

In-game: “Unlocked a new item.”

Sources:Achievements Challenges When Life Gives You Lemons

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Stage 1

Card Against Humanity
Next up
Complete When Life Gives You Lemons (challenge #12).
Start When Life Gives You Lemons from the Challenges menu and defeat Mom.
Each challenge has its own starting items and rules. The wiki page for the challenge has tips.
Sources:Achievements Challenges When Life Gives You Lemons