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Isaac Progression

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Unofficial fan project. Not affiliated with the developers of The Binding of Isaac.

Game facts are sourced from the Binding of Isaac Rebirth Wiki (CC BY-SA), and each guide links to its sources. Your progress is saved only in this browser.

Achievement

Euthanasia

Defeat Delirium as Lilith.

In-game: “Unlocked a new item.”

Sources:Achievements The Void Delirium

0 of 6 doneNext: The Womb

x

Stage 1any order

Azazel
Ready
Make 3 deals with the Devil in one run.
The Womb
Next up
Defeat Mom.
Reach Depths II and defeat Mom.
Sources:Achievements Womb

Stage 2any order

Blue Womb
Later
Defeat Mom's Heart 10 times.
After: The Womb
Mom's Heart defeats0 / 10
Lilith
Later
Defeat Ultra Greed as Azazel.
After: Azazel

Stage 3

New Area
Later
Defeat Hush.
After: The Womb, Blue Womb
Hush defeats0 / 1

Stage 4

Euthanasia
Later
Defeat Delirium as Lilith.
After: Lilith, The Womb, Blue Womb, New Area