The Womb
Next upDefeat Mom.
Reach Depths II and defeat Mom.
Sources:AchievementsWomb
Achievement
Defeat Mother as The Lost.
In-game: “Complete the Corpse with the Lost.”
Sources:AchievementsMotherCorpse
Defeat Mom.
Reach Depths II and defeat Mom.
Sources:AchievementsWomb
Defeat Mom's Heart 10 times.
After: The Womb
Defeat Satan 5 times.
After: The Womb
Defeat Hush 3 times.
After: The Womb, Blue Womb
Defeat The Lamb as Isaac.
After: The Womb, The Negative
Die in a Sacrifice Room while holding the Missing Poster.
After: Missing Poster
Defeat Mother as The Lost.
After: The Lost, A Secret Exit