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Isaac Progression

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Unofficial fan project. Not affiliated with the developers of The Binding of Isaac.

Game facts are sourced from the Binding of Isaac Rebirth Wiki (CC BY-SA), and each guide links to its sources. Your progress is saved only in this browser.

Achievement

Pandora's Box

Defeat The Lamb as Lazarus.

In-game: “Unlocked a new item.”

Sources:Achievements Dark Room The Lamb

0 of 4 doneNext: The Womb

x

Stage 1any order

Lazarus
Ready
Have 4 or more soul hearts at the same time.
The Womb
Next up
Defeat Mom.
Reach Depths II and defeat Mom.
Sources:Achievements Womb

Stage 2

The Negative
Later
Defeat Satan 5 times.
After: The Womb
Satan defeats0 / 5

Stage 3

Pandora's Box
Later
Defeat The Lamb as Lazarus.
After: Lazarus, The Womb, The Negative