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Isaac Progression

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Unofficial fan project. Not affiliated with the developers of The Binding of Isaac.

Game facts are sourced from the Binding of Isaac Rebirth Wiki (CC BY-SA), and each guide links to its sources. Your progress is saved only in this browser.

Achievement

Sigil of Baphomet

Complete Bloody Mary (challenge #37).

In-game: “Complete Challenge 37.”

Sources:Achievements Challenges Bloody Mary

0 of 7 doneNext: The Womb

x

Stage 1any order

Blood Bag
ReadyNeeds confirmation
Use the Blood Donation Machine 30 times.
Blood Donation Machine uses0 / 30
Lazarus
Ready
Have 4 or more soul hearts at the same time.
The Womb
Next up
Defeat Mom.
Reach Depths II and defeat Mom.
Sources:Achievements Womb

Stage 2any order

Bethany
Later
Defeat Mom's Heart or It Lives! on Hard mode as Lazarus without dying.
After: Lazarus, The Womb
It Lives!
Later
Defeat Mom's Heart 11 times.
After: The Womb
Mom's Heart defeats0 / 11

Stage 3

Bloody Mary
Later
Unlock Bethany, Blood Bag and It Lives!
After: Bethany, Blood Bag, It Lives!

Stage 4

Sigil of Baphomet
Later
Complete Bloody Mary (challenge #37).
After: Bloody Mary