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Isaac Progression

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Unofficial fan project. Not affiliated with the developers of The Binding of Isaac.

Game facts are sourced from the Binding of Isaac Rebirth Wiki (CC BY-SA), and each guide links to its sources. Your progress is saved only in this browser.

Achievement

Star of Bethlehem

Defeat Delirium as Bethany.

In-game: “Beat the Void with Bethany.”

Sources:Achievements The Void Delirium

0 of 6 doneNext: The Womb

x

Stage 1any order

Lazarus
Ready
Have 4 or more soul hearts at the same time.
The Womb
Next up
Defeat Mom.
Reach Depths II and defeat Mom.
Sources:Achievements Womb

Stage 2any order

Bethany
Later
Defeat Mom's Heart or It Lives! on Hard mode as Lazarus without dying.
After: Lazarus, The Womb
Blue Womb
Later
Defeat Mom's Heart 10 times.
After: The Womb
Mom's Heart defeats0 / 10

Stage 3

New Area
Later
Defeat Hush.
After: The Womb, Blue Womb
Hush defeats0 / 1

Stage 4

Star of Bethlehem
Later
Defeat Delirium as Bethany.
After: Bethany, The Womb, Blue Womb, New Area