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Isaac Progression

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Unofficial fan project. Not affiliated with the developers of The Binding of Isaac.

Game facts are sourced from the Binding of Isaac Rebirth Wiki (CC BY-SA), and each guide links to its sources. Your progress is saved only in this browser.

Character

Cain

Tainted version: Tainted Cain

Unlocking Cain

Achievement “Cain” #2

Hold 55 coins at the same time.

Completion marks

0 of 12 marks · 0 on Hard / Greedier. Click a mark to change it.

A Hard win counts as Normal too.

Sources:Completion Marks Hard mode Greed Mode

What the marks unlock

Heart (Hard)Glass BabyUnlocked a new co-player baby.
IsaacA Bag of PenniesUnlocked a new item.
SatanA Bag of BombsUnlocked a new item.
???Cain's EyeUnlocked a new item.
LambAbelUnlocked a new item.
Mega SatanGreen BabyUnlocked a new co-player baby.
Boss RushCain's Other EyeUnlocked a new item.
HushD12Unlocked a new item.
GreedEvil EyeUnlocked a new item.
Greed (Greedier)Sack of SacksUnlocked a new item.
DeliriumSilver DollarUnlocked a new item.
MotherGuppy's EyeComplete the Corpse with Cain.
BeastA Pound of FleshComplete the final chapter with Cain.

Unlocked by playing as Cain

Tainted CainOpen the hidden closet in Home as Cain.
Picky BabyEarn every completion mark on Hard mode as Cain.