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Isaac Progression

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Unofficial fan project. Not affiliated with the developers of The Binding of Isaac.

Game facts are sourced from the Binding of Isaac Rebirth Wiki (CC BY-SA), and each guide links to its sources. Your progress is saved only in this browser.

Character

Bethany

Tainted version: Tainted Bethany

Unlocking Bethany

Achievement “Bethany” #404

Defeat Mom's Heart or It Lives! on Hard mode as Lazarus without dying.

Completion marks

0 of 12 marks · 0 on Hard / Greedier. Click a mark to change it.

A Hard win counts as Normal too.

Sources:Completion Marks Hard mode Greed Mode

What the marks unlock

Heart (Hard)Wisp BabyBeat the game in Hard mode with Bethany.
IsaacBook of VirtuesComplete the Cathedral with Bethany.
SatanUrn of SoulsComplete Sheol with Bethany.
???Blessed PennyComplete the Chest with Bethany.
LambAlabaster BoxComplete the Dark Room with Bethany.
Mega SatanGlowing BabyDefeat Mega Satan with Bethany.
Boss RushBeth's FaithComplete Boss Rush with Bethany.
HushDivine InterventionComplete??? with Bethany.
GreedSoul LocketBeat Greed mode with Bethany.
Greed (Greedier)Vade RetroBeat Greedier mode with Bethany.
DeliriumStar of BethlehemBeat the Void with Bethany.
MotherRevelationComplete the Corpse with Bethany.
BeastJar of WispsComplete the final chapter with Bethany.

Unlocked by playing as Bethany

Tainted BethanyOpen the hidden closet in Home as Bethany.
Hope BabyEarn every completion mark on Hard mode as Bethany.